Autologous serum skin test in chronic spontaneous urticaria and its correlation with biochemical markers- A descriptive study from a tertiary hospital of North India

Autoimmune urticaria (AIU) is an important subset of chronic spontaneous (CSU) and can be relatively difficult to manage. Autologous serum skin test (ASST) has served as a useful bedside detect AIU its comparison with various blood biomarkers may unlock avenues in diagnosing autoimmune urticaria. Aim our study was assess role ASST CSU correlation relevant biomarkers. It hospital-based which 58 patients were enrolled. done all routine investigations including Absolute Eosinophil Count (AEC), Thyroid stimulating hormone (TSH) Immunoglobulin E(IgE). positive 44.8% out patients. showed longer disease duration, higher severity more generalised than the negative group. AEC lower, although statistically insignificant (284.21±57.43 cells/ul) compared (310.64±71.05 (p=0.131). TSH on other hand comparable values both groups (p=0.744). Mean IgE significant difference between those who (297.96 ±42.34 IU/ml) vs negative. (323.57 ±44.16 (p=0.029*). serve diagnose often severe prolonged well being refractory conventional treatment. Lower complement diagnosis